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Tummy (abdominal) pain Vincristine can temporarily stop the normal muscle contractions of the bowel. You may report side effects to FDA at 1-800-FDA-1088. Along with their needed effects, medicines like vincristine can sometimes cause unwanted effects such as blood problems, nervous system problems, loss of hair, and other side effects. The drug can interact with the pet’s nervous system and can give rise to seizures and neurological disorders. Call your doctor right away if any of these effects bother you, do not go away, or get very bad. If you notice any other effects, check with your healthcare professional. Advertising revenue supports our not-for-profit mission. This medicine often causes a temporary loss of hair. Vincristine is a chemotherapy drug. Vomiting 5. Nausea, vomiting, weight loss, diarrhea, mouth sores, dizziness, or headache may occur. Possible Side Effects: • Decreased sensation and numbness in fingers and toes may become progressively worse with repeated doses. The following side effects are common (occurring in greater than 30%) for patients taking Vincristine: Hair loss (in 20-70% of patients) may be partial or complete hair loss Call your doctor if you have any unusual problems while taking this medication. Medically reviewed by Drugs.com. Marqibo (VinCRIStine Sulfate Liposome Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. To reduce the potential for fatal medication errors due to incorrect route of administration proper dilution, product labeling and packaging is necessary. Other side effects not listed may also occur in some patients. Jaw pain, pharyngeal pain, parotid gland pain, bone pain, back pain, limb pain, and myalgias have been reported; pain in these areas may be severe. These and others are described below. Read more about the prescription drug VINCRISTINE - INJECTION. Local injection of hyaluronidase and the application of moderate heat to the area of leakage help disperse the drug and are thought to minimize discomfort and the possibility of cellulitis. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online, dizziness or lightheadedness when getting up from a lying or sitting position, hallucinations (seeing, hearing, or feeling things that are not there). Drug information provided by: IBM Micromedex. Find out about how you have it, possible side effects and other important information. Applies to vincristine: compounding powder, intravenous solution, Frequency not reported: Acute shortness of breath, severe bronchospasm, dyspnea[Ref], Common (1% to 10%): Constipation (may take the form of upper colon impaction), paralytic ileus, abdominal cramps, Uncommon (0.1% to 1%): Nausea, vomiting, diarrhea, anorexia, stomatitis, oral ulceration, intestinal necrosis and/or perforation, abdominal cramps, abdominal distension, weight loss, Frequency not reported: Paralytic ileus (particularly in young children and in the elderly), pancreatitis[Ref], Frequency not reported: Anemia, leukopenia, thrombocytopenia[Ref], Frequency not reported: Hypertension, hypotension[Ref], Frequency not reported: Transient cortical blindness, optic atrophy with blindness, diplopia, ptosis, photophobia, visual hallucinations[Ref], Frequency not reported: Polyuria, oliguria, nocturia, dysuria, urinary retention, testicular pain[Ref], Frequency not reported: Second malignancies[Ref], Rare (0.01% to 0.1%): Allergic-type reactions (e.g., anaphylaxis)[Ref], Frequency not reported: Hepatic veno-occlusive disease, hepatitis[Ref], Frequency not reported: Neurotoxicity is the most common dose-limiting side effect of this drug. 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